Regenerative Medicine

Stem Cell Therapy for Shoulder Pain

Stem cell therapy for shoulder pain provides a regenerative approach to treating rotator cuff tears, shoulder osteoarthritis, labral tears, and chronic tendinopathy. Rather than surgically repairing or replacing damaged tissue, stem cell injections deliver concentrated regenerative cells directly to the injury site.

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Conceptual illustration

Accepting new patientsNorth Georgia East TennesseeFind your clinic

Updated September 2026

Conditions Treated

Partial rotator cuff tears, shoulder osteoarthritis, labral tears, biceps tendinopathy, AC joint arthritis, frozen shoulder (adhesive capsulitis), chronic shoulder pain after previous surgery

Joint Pain

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The treatment explained

How It Works

Stem cells harvested from bone marrow are concentrated and injected into the shoulder joint and surrounding structures under ultrasound guidance. The regenerative cells differentiate into tendon, cartilage, and other tissue types needed for repair. Growth factors in the concentrate reduce inflammation and stimulate the body's natural healing cascade.

Conceptual illustration: Shoulder with highlighted rotator cuff and labrum

Treatment day

What to Expect

60-90 minute procedure. Local anesthesia with optional light sedation. You will wear a sling for a few days. Expect mild shoulder swelling for 1-2 weeks.

Afterward

Recovery

Sling use for 3-5 days. Gentle range-of-motion exercises begin at 1-2 weeks. Progressive strengthening at 4-6 weeks. Full activity at 8-12 weeks. Physical therapy recommended.

Duration of Relief

In the shoulder, the result depends on the size of the tear, how long it has been there, and the quality of the surrounding tendon. That is what your imaging and the consultation are for.

Regulatory status. FDA approvals apply to specific products and conditions. For example, Ryoncil is approved for steroid-refractory acute graft-versus-host disease in children aged 2 months and older.[1] That approval does not cover the orthopedic treatments described here. A treatment that concentrates your own bone marrow or adipose tissue is not FDA-approved for rotator cuff or tendon conditions, and we will go through what that means for you, and what the alternatives are for your diagnosis.

You will wear a sling for a few days afterwards. The 60-90 minute procedure is done under local anesthesia with optional light sedation, and mild shoulder swelling is expected for 1-2 weeks. Whether it is an appropriate option depends on your imaging and what you have already tried, so request an appointment to go through both. Request an appointment

Limitless Performance Medicine

Our regenerative medicine program is powered by Limitless Performance Medicine — advanced regenerative protocols delivered with interventional pain precision. Limitless is a separate practice founded and owned by Dr. Joshua Hare, IPC's Founder & Medical Director.

Learn More at Limitless →

References

Clinical sources for this page.

U.S. Food and Drug Administration. FDA Approves First Mesenchymal Stromal Cell Therapy to Treat Steroid-Refractory Acute Graft-Versus-Host Disease. Immediate release, December 18, 2024. Back to first citation ↑

Five clinics

Book a visit

Our fellowship-trained physicians are accepting new patients at five clinics: Dalton, Ringgold, Cleveland, Farragut and Oak Ridge.

Request a callback Call (706) 847-0826